🧪 B12 10ml (Methylated): Endocrine Research Profile
Metabolic Enzyme Cofactor (Active Form): Methylcobalamin is the biologically active, methylated coenzyme form of Vitamin B12. Unlike Cyanocobalamin, which requires a multi-step enzymatic conversion to remove a cyanide molecule, B12 10ml (Methylated) is a “ready-to-use” organometallic compound. In laboratory research, it is the primary focus for investigating methylation pathways and the direct conversion of homocysteine to methionine via methionine synthase.
🧠 Neurological Maintenance and Myelination: Research profiles indicate that B12 10ml (Methylated) is fundamental in investigating the preservation of the myelin sheath. Studies focus on its unique ability to cross the blood-brain barrier more effectively than other cobalamins, influencing the synthesis of phospholipids required for neuronal structural integrity and nerve regeneration.
🩸 Hematopoietic Proliferation: B12 10ml (Methylated) is utilized in hematology research to observe the maturation of erythrocytes without the metabolic lag associated with pro-vitamin conversion. Laboratory evaluations explore its role in facilitating rapid DNA synthesis and proper cell division within bone marrow, specifically focusing on its interaction with the folate cycle.
⚡ Mitochondrial Energy Dynamics: As an active methyl donor, B12 10ml (Methylated) is studied for its impact on cellular energy production. Researchers monitor how its presence influences the breakdown of amino acids and its synergy with the citric acid cycle for efficient ATP generation and the reduction of oxidative stress within the mitochondria.
✅ B12 10ml (Methylated) Product Specifications
| Specification | Detail |
| Product Name | B12 10ml (Methylated) |
| Molecular Formula | C63H91CoN13O14P |
| Molecular Weight | 1344.38 g/mol |
| Concentration | 1000 mcg/mL (Total 10mg per 10mL vial) |
| CAS Number | 13422-55-4 |
| Appearance | Clear, dark red aqueous solution |
| Solubility | Highly soluble in water and saline |
❄️ Product Care & Handling Guidelines
Light Sensitivity (Photolysis): Methylcobalamin is significantly more light-sensitive than Cyanocobalamin. Exposure to light will cause the methyl group to dissociate. The 10ml vial MUST be stored in total darkness or a light-blocking opaque secondary container at all times.
Temperature Regulation: Store at controlled refrigerated temperatures (2°C to 8°C) for long-term stability. While it can remain at room temperature for short periods during research, heat accelerates degradation. Do not freeze, as this can cause the solution to precipitate.
Aseptic Handling: As a multi-use 10ml research vial, maintain strict sterile techniques. Ensure the rubber stopper is disinfected with 70% isopropyl alcohol before every access to prevent microbial contamination of the research medium.
📚 References & Resources
NCBI PubMed: https://pubmed.ncbi.nlm.nih.gov/11330922/ (Methylcobalamin in Nerve Repair)
NCBI PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC4433432/ (Bioavailability of Cobalamins)
PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/Methylcobalamin
Mayo Clinic: https://www.mayoclinicproceedings.org/ (Clinical Research Significance)
⚠️ Laboratory Research Use Only Notice
This B12 10ml (Methylated) profile is strictly intended for in vitro and non-clinical laboratory research purposes only. It is categorized as a research compound and is not intended for human consumption, veterinary diagnostic, or therapeutic use. Statements regarding the biochemical potential of Vitamin B12 have not been evaluated by the Food and Drug Administration (FDA).
