🧪 Ipamorelin 5mg: Endocrine Research Profile
The Ipamorelin 5mg (sequence: Aib-His-D-2-Nal-D-Phe-Lys-NH2) is a synthetic pentapeptide derived from the GHRP-1 family. Researchers utilizing the Ipamorelin 5mg focus on its unique ability to stimulate the release of growth hormone (GH) from the pituitary gland with high specificity, distinguishing it from other agents that may influence stress hormones.
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Selective Pituitary Signaling: The Ipamorelin 5mg peptide is primarily researched for its ability to induce a single episode of GH release without stimulating the secretion of adrenocorticotropic hormone (ACTH) or cortisol.
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Ghrelin Receptor Agonism: Studies on the Ipamorelin 5mg indicate that it binds selectively to the ghrelin receptor, facilitating research into appetite regulation and fat processing in cellular analogs.
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Musculoskeletal Homeostasis: The Ipamorelin 5mg formulation is investigated for its role in counteracting the catabolic effects of glucocorticoids on skeletal muscle and bone formation.
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Gastric Motility Research: Laboratory evaluations of the Ipamorelin 5mg explore its capacity to improve gastric emptying and reverse symptoms of delayed gastrointestinal transit in postoperative models.
🔬 Key Research Applications of Ipamorelin 5mg
This specific Ipamorelin 5mg peptide is a primary focus for research models investigating:
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🧬 Bone Development & Density: Studies on the Ipamorelin 5mg look at its effects on longitudinal bone growth rates and the stimulation of periosteal bone formation in animal models.
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🏃 Muscle Preservation Signaling: Research into the Ipamorelin 5mg includes evaluations of the maximum tetanic tension of muscle fibers and the mitigation of steroid-induced muscular atrophy.
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🛡️ Nitrogen Balance Stabilization: Investigations into the biochemical properties of the Ipamorelin 5mg focus on its capacity to neutralize negative nitrogen balance in models of accelerated wasting.
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🔥 Selective Endocrine Dynamics: Evaluation of the Ipamorelin 5mg for its ability to increase plasma growth hormone levels while maintaining stable levels of FSH, LH, and TSH.
✅ Ipamorelin 5mg Product Specifications
| Specification | Detail |
| Product Name | Ipamorelin 5mg |
| Molecular Formula | C38H49N9O5 |
| Molecular Weight | 711.85 g/mol |
| Concentration | 5 mg per vial |
| Sequence | Aib-His-D-2-Nal-D-Phe-Lys-NH2 |
| Appearance | White to off-white lyophilized powder |
| Solubility | Soluble in sterile water or PBS |
❄️ Product Care & Handling Guidelines
Proper storage is required to maintain the molecular integrity of the Ipamorelin 5mg polypeptide.
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Unreconstituted (Powder): Store the Ipamorelin 5mg in a dry, dark environment. Long-term storage is optimal at -20 degrees C for maximum stability. 3
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Reconstituted (Liquid): Refrigerate the Ipamorelin 5mg at 2 degrees C to 8 degrees C immediately; researchers typically use the solution within 2 to 7 days for maximum potency.
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Handling Note: Peptides like the Ipamorelin 5mg are sensitive to mechanical stress. Use gentle swirling during reconstitution and avoid repeated freeze-thaw cycles.
📚 References & Resources
PubMed: https://pubmed.ncbi.nlm.nih.gov/9849822/
PubMed: https://pubmed.ncbi.nlm.nih.gov/11735244/
NCBI PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC7108996/
PubMed: https://pubmed.ncbi.nlm.nih.gov/19289567/
NCBI PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC4863553/
⚠️ Laboratory Research Use Only Notice
The Ipamorelin 5mg product is strictly intended for in vitro and non-clinical laboratory research purposes only. It is not for human consumption, veterinary diagnostic, or therapeutic use. Statements regarding the biochemical potential of the Ipamorelin 5mg have not been evaluated by the FDA. Researchers must follow established laboratory safety and ethical standards.
