🧪 CJC-1295 No DAC 5mg: Endocrine Research Profile
CJC-1295 No DAC 5mg is a synthetic polypeptide that incorporates four key amino acid substitutions at positions 2, 8, 15, and 27 to improve stability. Researchers utilizing CJC-1295 No DAC 5mg focus on its ability to mimic natural GHRH signaling while resisting rapid cleavage by dipeptidyl peptidase-4 (DPP-4).2
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Pulsatile Growth Secretion: The CJC-1295 No DAC 5mg peptide is primarily researched for its ability to trigger episodic, pulsatile growth hormone release, which facilitates research into natural endocrine rhythms.3
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GHRH Receptor Specificity: Studies on CJC-1295 No DAC 5mg indicate that it binds with high affinity to GHRH receptors on somatotrophs, activating the adenylate cyclase-cAMP pathway.4
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IGF-1 Elevation Research: The CJC-1295 No DAC 5mg formulation is investigated for its role in secondary hepatic production of Insulin-like Growth Factor-1, a key mediator of anabolic signaling.5
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Metabolic Signaling: Laboratory evaluations of CJC-1295 No DAC 5mg explore its influence on lipid oxidation, nitrogen retention, and the preservation of lean muscle density in animal analogs.
🔬 Key Research Applications of CJC-1295 No DAC 5mg
This specific CJC-1295 No DAC 5mg peptide is a primary focus for research models investigating:
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🧬 Soft Tissue Regeneration: Investigations into the effects of CJC-1295 No DAC 5mg on accelerating the repair of connective tissues, collagen synthesis, and wound healing kinetics.6
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🏃 Musculoskeletal Homeostasis: Research into CJC-1295 No DAC 5mg includes evaluations of protein synthesis pathways and the mitigation of muscular wasting in stress-induced models.7
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🛡️ Sleep and Circadian Rhythms: Investigations into the biochemical properties of CJC-1295 No DAC 5mg focus on its capacity to improve slow-wave sleep patterns via GH-mediated pathways.
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🫀 Cardiac Tissue Support: Evaluation of CJC-1295 No DAC 5mg for its potential to support myocardial repair and influence ejection fraction metrics following experimental ischemic events.
✅ CJC-1295 No DAC 5mg Product Specifications
| Specification | Detail |
| Product Name | CJC-1295 No DAC 5mg |
| Molecular Formula | C152H252N44O42 |
| Molecular Weight | 3367.95 g/mol |
| Concentration | 5 mg per vial |
| Sequence | Tyr-D-Ala-Asp-Ala-Ile-Phe-Thr-Gln-Ser-Tyr-Arg-Lys-Val-Leu-Ala-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Leu-Ser-Arg-NH2 |
| Appearance | White lyophilized powder |
| Solubility | Soluble in sterile water or PBS |
❄️ Product Care & Handling Guidelines
Proper storage is essential to maintain the molecular integrity of the CJC-1295 No DAC 5mg polypeptide synthesis.
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Unreconstituted (Powder): Store CJC-1295 No DAC 5mg in a cool, dry environment. Long-term storage is optimal at -20 degrees C to -80 degrees C.
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Reconstituted (Liquid): Mixed CJC-1295 No DAC 5mg solution should be refrigerated at 2 degrees C to 8 degrees C and used within 7 to 10 days for maximum potency.
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Handling Note: Peptides in the CJC-1295 No DAC 5mg synthesis are sensitive to mechanical stress. Use gentle swirling during reconstitution and avoid repeated freeze-thaw cycles.
📚 References & Resources
NCBI PubMed: https://pubmed.ncbi.nlm.nih.gov/16352683/
NCBI PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC2787983/
PubMed: https://pubmed.ncbi.nlm.nih.gov/17018654/
NCBI PubMed: https://pubmed.ncbi.nlm.nih.gov/16822960/
PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/CJC1295-Without-DAC
⚠️ Laboratory Research Use Only Notice
The CJC-1295 No DAC 5mg product is strictly intended for in vitro and non-clinical laboratory research purposes only. It is not for human consumption, veterinary diagnostic, or therapeutic use. Statements regarding the biochemical potential of CJC-1295 No DAC 5mg have not been evaluated by the Food and Drug Administration (FDA). Researchers must follow established laboratory safety and ethical guidelines.
