🧪 Semax 10mg: Neuroprotective Research Profile
Semax 10mg is a synthetic heptapeptide (sequence: Met-Glu-His-Phe-Pro-Gly-Pro) precision-engineered for advanced studies targeting neuropsychotropic and neuroprotective signaling. Developed originally at the Institute of Molecular Genetics, this compound incorporates a Pro-Gly-Pro tripeptide at its C-terminus, which provides enhanced resistance to enzymatic degradation and maintains biological activity across a wide range of physiological conditions.
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Neurotrophin Modulation: Primarily researched for its ability to stimulate the synthesis of Brain-Derived Neurotrophic Factor (BDNF) and Nerve Growth Factor (NGF) in brain tissues.
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Monoaminergic System Influence: Evaluated for its role in modulating dopaminergic and serotonergic systems, potentially influencing focus, motivation, and emotional stability in stress models.
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Cerebrovascular Support: Studied for its effects on improving cerebral blood flow, oxygen delivery, and protecting the blood-brain barrier (BBB) integrity.
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Anti-Inflammatory Action: Investigated for its ability to reduce pro-inflammatory cytokines such as IL-6 and suppress oxidative stress in damaged neural tissues.
🔬 Key Research Applications of Semax 10mg
This specialized heptapeptide is a primary focus for research models investigating:
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🧠 Cognitive Enhancement: Investigations into the peptide’s influence on memory formation, attention span, and information retention in nootropic research.
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🌪️ Ischemic and TBI Recovery: Evaluation of neuroprotective effects in models of ischemic stroke and traumatic brain injury (TBI) to observe reduced infarct size and accelerated functional recovery.
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⚡ Neurodevelopmental Models: Studies focusing on the potential therapeutic pathways in ADHD and Rett syndrome through the augmentation of dopamine and BDNF signaling.
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👁️ Optic Nerve Preservation: Research into the peptide’s efficacy in protecting against degenerative diseases of the optic nerve and maintaining neural health in ocular models.
✅ Semax 10mg Product Specifications
| Specification | Detail |
| Molecular Formula | C37H51N9O10S |
| Molecular Weight | 813.93 Da |
| Concentration | 10 mg per vial |
| Sequence | Met-Glu-His-Phe-Pro-Gly-Pro |
| Appearance | Lyophilized white powder |
| Format | Lyophilized powder for reconstitution |
| Solubility | Soluble in water (up to 100 mg/ml) or PBS |
❄️ Product Care & Handling Guidelines
Proper storage is essential to maintain the molecular integrity and potency of the Semax heptapeptide.
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Unreconstituted (Powder): Store in a cool, dry environment away from light. Long-term storage requires temperatures of -20°C to -80°C. Peptides in powder form are stable at room temperature for up to 3 weeks during transit.
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Reconstituted (Liquid): Must be refrigerated at 2°C to 8°C immediately; use within 2 to 7 days for optimal stability. For longer storage, freeze aliquots at -20°C to avoid repeated freeze-thaw cycles.
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Handling Note: Peptides are sensitive to mechanical stress. Avoid vigorous shaking during reconstitution; instead, use gentle swirling until the powder is fully dissolved.
📚 References & Resources
📚 References & Resources
PubMed: https://pubmed.ncbi.nlm.nih.gov/16996037/
NCBI PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC3987924/
PubMed: https://pubmed.ncbi.nlm.nih.gov/16996699/
NCBI PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC11498467/
PubMed: https://pubmed.ncbi.nlm.nih.gov/16635254/
⚠️ Laboratory Research Use Only Notice
This product is strictly intended for in vitro and non-clinical laboratory research purposes only. It is not for human consumption, veterinary diagnostic, or therapeutic use. Statements regarding the biochemical potential of this compound have not been evaluated by the Food and Drug Administration (FDA). Researchers must adhere to established laboratory safety and ethical guidelines.