🧪 VIP 10mg: Endocrine Research Profile

• VPAC Receptor Agonism: VIP 10mg acts as a dual agonist for the G protein-coupled receptors VPAC1 and VPAC2, stimulating the adenylate cyclase-cAMP signaling pathway to regulate smooth muscle relaxation and immune cell activity.

• Circadian Rhythm Synchronization: Research indicates that VIP is a primary synchronizing agent in the brain, facilitating studies into how neurons in the suprachiasmatic nucleus coordinate light cues with biological timing.

• Immunomodulatory Signaling: Laboratory evaluations of VIP 10mg explore its capacity to act as an anti-inflammatory agent by inhibiting the production of pro-inflammatory cytokines and promoting the differentiation of regulatory T cells (Tregs).

• Cardiovascular and Pulmonary Dynamics: This peptide is researched for its potent inotropic effects on cardiac tissue and its ability to reduce pulmonary vascular resistance, serving as a model for investigating pulmonary hypertension and respiratory airflow.

✅ VIP 10mg Product Specifications

❄️ Product Care & Handling Guidelines

• Unreconstituted (Powder): Store VIP 10mg in a dry, dark environment. For long-term preservation, storage at -20°C to -80°C is recommended to prevent oxidation, particularly of the Methionine (M) residue.

• Reconstituted (Liquid): VIP is highly unstable in solution. Reconstituted aliquots should be used immediately or stored at 2°C to 8°C for no more than 48 hours. For storage up to 7 days, keep at -20°C and avoid repeated freeze-thaw cycles.

• Handling Note: VIP has a high propensity to adsorb to plastic and glass surfaces at low concentrations. Researchers often use siliconized vials or add a carrier protein (like 0.1% BSA) to prevent significant peptide loss.

• ---

  📚 References & Resources

  1. NCBI PubMed: https://pubmed.ncbi.nlm.nih.gov/19173226/ (Signaling Pathways)

  2. NCBI PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC6743256/ (Physiology Advances)

  3. PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/Vasoactive-Intestinal-Peptide

  4. Oxford Academic: https://academic.oup.com/cardiovascres/article/49/1/27/293330 (Cardiovascular Effects)

  5. Frontiers in Microbiology: https://www.frontiersin.org/articles/10.3389/fmicb.2019.02689 (Metabolic/Gut Microbiota)

⚠️ Laboratory Research Use Only Notice

The VIP 10mg product is strictly intended for in vitro and non-clinical laboratory research purposes only. It is not for human consumption, veterinary diagnostic, or therapeutic use. Statements regarding the biochemical potential of VIP 10mg have not been evaluated by the Food and Drug Administration (FDA).