GLP-3 Retatrutide 5mg

🧪 GLP-3 Retatrutide 5mg: Metabolic Research Profile

GLP-3 Retatrutide 5mg is a synthetic 39-amino acid polypeptide precision-engineered for studies involving the simultaneous activation of GIP, GLP-1, and glucagon receptors.² Researchers utilizing GLP-3 Retatrutide 5mg focus on its unique chimeric structure, which incorporates a C-20 fatty diacid moiety to enhance its stability and metabolic bioactivity in research settings.³

• Triple Receptor Affinity: The GLP-3 Retatrutide 5mg peptide is researched for its high affinity at GIP receptors (factor of 8.9) and potent agonism at both GLP-1 and GCG receptors.

• Glucagon Receptor Signaling: Unlike earlier dual agonists, GLP-3 Retatrutide 5mg allows for the study of glucagon-mediated energy expenditure and lipid oxidation pathways.⁴

• Enzymatic Stability: Featuring structural modifications that resist dipeptidyl peptidase-4 (DPP-4) degradation, GLP-3 Retatrutide 5mg facilitates an extended biological half-life of approximately 6 days in research models.

• Metabolic Flexibility: Laboratory evaluations of GLP-3 Retatrutide 5mg explore its ability to modulate hepatic fat content and stabilize glucose-dependent insulin secretion.

🔬 Key Research Applications of GLP-3 Retatrutide 5mg

This peptide is primarily used in laboratory models investigating:

• 🧬 Synergistic Homeostasis: Studies on GLP-3 Retatrutide 5mg look at the effects of triple agonism on energy balance and metabolic markers compared to mono- or dual-agonists.

• 🧠 Hypothalamic Signaling: Research into GLP-3 Retatrutide 5mg includes evaluations of the hypothalamic appetite centers and neuroplasticity in energy regulation models.

• 🛡️ Hepatoprotective Research: Investigations into the biochemical properties of GLP-3 Retatrutide 5mg focus on liver fat reduction and markers of metabolic dysfunction-associated steatotic liver disease (MASLD).

• 🫀 Cardiometabolic Dynamics: Evaluation of GLP-3 Retatrutide 5mg for its influence on vascular signaling and blood pressure stabilization in research analogs.

✅ GLP-3 Retatrutide 5mg Product Specifications

❄️ Product Care & Handling Guidelines

Proper storage is required to maintain the molecular integrity of the GLP-3 Retatrutide 5mg polypeptide.

• Unreconstituted (Powder): Store GLP-3 Retatrutide 5mg in a cool, dry environment. Long-term storage is optimal at -20°C to -80°C.

• Reconstituted (Liquid): Refrigerate GLP-3 Retatrutide 5mg at 2°C to 8°C immediately; researchers typically use within 14 to 30 days for maximum stability.

• Handling Note: Peptides like GLP-3 Retatrutide 5mg are sensitive to mechanical stress. Use gentle swirling during reconstitution; avoid vigorous shaking to prevent peptide denaturation.

📚 References & Resources

NCBI PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC11271400/

PubMed: https://pubmed.ncbi.nlm.nih.gov/40291085/

NCBI PMC: https://pmc.ncbi.nlm.nih.gov/articles/PMC12026077/

PubChem: https://pubchem.ncbi.nlm.nih.gov/compound/Retatrutide

NCBI PubMed: https://pubmed.ncbi.nlm.nih.gov/40741227//

⚠️ Laboratory Research Use Only Notice

The GLP-3 Retatrutide 5mg product is strictly intended for in vitro and non-clinical laboratory research purposes only. It is not for human consumption, veterinary diagnostic, or therapeutic use. Statements regarding the biochemical potential of GLP-3 Retatrutide 5mg have not been evaluated by the Food and Drug Administration (FDA). Researchers must follow established laboratory safety protocols.